Akademik Dersler - İçerik

Explain the definition and historical development of pharmaceutical chemistry.
Define Pharmaceutical Chemistry.
Define Medicinal Chemistry.
Explain the relationship between Pharmaceutical Chemistry and other sciences.
Explain the historical development of Pharmaceutical Chemistry.
Explains innovative developments in the field of Medicinal Chemistry.
Explain structure-nonspecific drugs.
Identify structure-nonspecific drugs.
List the properties of structure-nonspecific drugs.
Explain structure-specific drugs.
List the properties of structure-specific drugs.
Explain the effects of structural changes on biological activity.
Explain chemical bonds in drug-receptor interactions.
Explain the importance of bonds in drug-receptor interactions.
List the types of bonds that are important in drug-receptor interactions.
Explain drug-receptor compatibility and stereochemical factors.
Classify isomers.
Determines the stereochemistry of a drug molecule.
Explain the effects of stereochemistry on biological activity.
Explains stereoselective activity.
Explain the resolution of racemic mixtures.
Explain the physicochemical properties and pharmacological activity.
Explains solubility and its effects on biological activity.
Explain the partition coefficient and its effects on biological activity.
Determines the ionization patterns of the drug molecule.
Explains the pKa value and the factors affecting pKa.
Explain structural features and pharmacological activity.
Explain steric properties.
Classify bioisosteres.
Explain the effects of functional groups on pharmacological activity.
Explain Quantitative Structure-Activity Relationships (QSAR).
Explain the important methods in QSAR studies.
List the methods used in QSAR studies.
Explain Phase I Reactions.
List the types of phase I reactions.
Indicates Phase I reaction pathways of drug molecules.
Explains the chemical structures and properties of metabolites formed as a result of the metabolism of drug molecules.
Explain Phase II Reactions.
List the types of phase II reactions.
It specifies which Phase II reaction pathways drug molecules will follow.
Explain the chemical structures and properties of conjugates formed as a result of the metabolism of drug molecules.
Explain the effects of stereochemical factors on metabolism.
Explain substrate stereoselectivity.
Explain product (metabolite) stereoselectivity.
Explain substrate-product stereoselectivity.
Explain enzymatic inversion.
Explain drug metabolism studies.
Explains the basic stages of a classical drug metabolism study.
List the methods used in the quantitative determination of drug metabolites.
Explain drug development methods.
Explain the methods used to find the lead compound.
Explain the routes used in the optimization of the lead compound.
Explain Combinatorial Chemistry.
Define Combinatorial Chemistry.
Explains the creation of combinatorial libraries.
Explains the discovery of the active compound from the mixture obtained by combinatorial methods.
Be able to perform synthesis applications.
Determine the appropriate method for the synthesis of the target compound.
Explain the reaction conditions of the synthesis.
Explain the reaction equation and mechanism of synthesis.
Explains the properties and purposes of the chemical substances required for synthesis.
Explain the properties and uses of devices required for synthesis.
Synthesizes the target compound.
Be able to perform separation and purification applications.
Applies the appropriate process to remove the synthesis product from the reaction medium.
Explains the physical and chemical properties of the synthesis product.
Calculates the theoretical, practical and percentage yield of the synthesis product.
The synthesis product is crystalline.
Be able to perform IR Spectroscopy applications.
Lists the estimated IR data of the compounds.
It determines which functional groups the bands in the IR spectrum belong to.
Determine the structure by interpreting IR spectra.
Be able to perform 1H NMR Spectroscopy applications.
Lists the predicted 1H-NMR data of the compounds.
It determines which protons the peaks observed in 1H-NMR spectra belong to.
Determine the structure by interpreting 1H-NMR spectra.
Be able to perform mass spectroscopy applications.
Lists the predicted MS data of the compounds.
It determines which parts the peaks observed in the mass spectrum belong to.
It determines the molecular ion peak in mass spectra.
It determines the main peak in mass spectra.
Interpret the mass spectra of compounds.
Be able to determine physical properties.
It distinguishes the sample by color, odor, taste and appearance.
Determines the melting point of the sample.
Determines the solubility class of the sample.
Be able to determine chemical properties.
Applies combustion test to the sample and interprets the results.
Detects the presence of nitrogen/sulfur/halogen in the sample.
Determines the acidic/basic character of the laboratory sample.
Be able to perform functional group analyses.
Distinguishes recognition tests belonging to functional groups in the compound.
Applies functional group recognition tests to the sample.
Be Able to Perform Special Diagnostic Reactions.
Identifies the specific diagnostic reaction that may be applied to the compound.
Applies a sample-specific diagnostic reaction.
Be able to perform titration methods.
List the titrimetric methods that can be applied to the compound.
Prepares the necessary solutions for the titrimetric method that can be applied to the sample.
Lists the chemicals required for the titrimetric method to be applied to the sample.
Explains the properties and intended uses of the chemical substances required for the titrimetric method to be applied to the sample.
Determines the appropriate ambient temperature for the titrimetric method to be applied to the sample.
Determines the potency of the compound.
Explains the reaction equation and mechanism of the titrimetric method to be applied to the sample.
Applies the titration method.
Determines the purity of the sample.
Be able to perform Instrumental Analysis Application.
List the instrumental analysis methods included in pharmacopoeias.
Determines the purity of an active pharmaceutical ingredient using spectrophotometry.