Akademik Dersler - İçerik

will be able to describe and compare computerized methods in pharmaceutical and medicinal chemistry
Evaluates the place and importance of Computer Methods in Pharmaceutical and Medicinal Chemistry in drug design.
will be able to interpret the structure of the receptor by acting on the structure of the affecting molecules.
comments target-based (Ligand-based) design
justifies traditional (2D) quantitative structure activity relationships.
will be able to develop Pharmacofor Analysis
design 3D Quantitative StructureActivity Relationships.
customize CoMFA and CoMSIA Methods.
propose the 4-, 5- and 6-Dimensional Quantitative Structure Activity Relationships
propose the 4-, 5- and 6-Dimensional Quantitative Structure Activity Relationships
will be able to design molecules that can be effective by actiing on the known receptor structure.
Evaluate the Receptor Based Design
Apply molecular modeling
Uses docking and imaging
Associate molecular mechanics and molecular dynamics methods
justify the virtual screening of drug candidate molecules.
Analyze the QSAR and docking methods using the relationships between structure and activity
will be able to develop the pharmacological modeling (the development of a molecular model of the drug with the desired pharmacological properties such as hydrophobicity and hydrogen bonding capacity, and the search for the most suitable drug molecule in nature).
Uses and adapts the data banks containing detailed information of candidate drug molecules
carry out the high throughput screening (HTS)
develops de novo (synthetic) drug design
proposes the computer aided drug design (CADD) of enzyme inhibitors as drug targets