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About the Programme Academic Staff Program Qualifications Lessons Matrix of Course & Program Qualifications Turkish Qualifications Framework (TQF) TQF & Program Qualifications
  1. Graduate School
  2. Department of Pharmaceutical Chemistry
  3. PhD in Pharmaceutical Chemistry
  4. Course Structure Diagram with Credits
  5. Peptide Syntheses
  6. Description
  • Description
  • Learning Outcomes
  • ECTS Credit Load
  • Course's Contribution to Program
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Last Updated: 30/09/2026

Code - Course Title Course Type Laboratory + Practice ECTS
FKM620 - Peptide Syntheses II. SEMESTER 3 +0 7.5
Language of Instruction Türkçe
Course Type Elective Courses
Course Instructor(s) PROF. DR. LEYLA YURTTAŞ
Mode of Delivery The mode of delivery of this course is face to face
Place of Delivery
Used Educational Platforms
Prerequisites There is no prerequisite or co-requisite for this course.
Courses Recomended Pharmaceutical Chemistry I, Pharmaceutical Chemistry II, Pharmaceutical Chemistry III, Pharmaceutical Chemistry IV
Recommended Resources Akgün, H., Balkan, A., Bilgin, A.A. ve arkadaşları., Farmasötik Kimya. Ankara: Hacettepe Üniversitesi, ISBN: 975-491-171-1. 2004. Akı-Şener, E., Yalçın, İ., Farmasötik/Medisinal Kimya’da İlaç Etken Madde Tasarım Yöntemleri-1, Kantitatif Yapı-Etki İlişkileri Analizleri (QSAR). Ankara: Ankara Üniversitesi Eczacılık Fakültesi Yayınları No: 86, 2003. Bilgin, A.A., Tozkoparan, B. Örneklerle Organik Kimya Nomenklatürü. Ankara: Hacettepe Üniversitesi Yayınları, ISBN: 978-975-491-266-1. 2008.Block, H.J., Beale, Jr, M.J., Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry-Twelfth Edition. ISBN-13: 978-81-8473-396-9, Published by Wolters Kluwer (India) Pvt. Ltd., New Delhi., 2010.Ergenç, N., Gürsoy, A., Ateş, Ö. Farmasötik Kimya Ders Kitabı (Medisinal Kimya) Cilt I. İstanbul: İstanbul Üniversitesi Yayın No: 4094, Eczacılık Fakültesi Yayın No: 72, ISBN 975-404-506-2. 1997. Gringuaz, A., Introduction to Medicinal Chemistry. ISBN: 0-471-18545-0, Wiley-VCH, Inc., USA. 1997.Ishar, M.P.S., Faruk, A., Syntheses of Organic Medicinal Compounds, ISBN 1-84265-280-X Alfa Science International, 7200 The Quorum, Oxford Business Part North Garsington Road, Oxford OX4 2JZ, U.K. p: 206, 2006.Kar, A., Medicinal Chemistry., Anshan Ltd. 6 Newlands Road Tunbridge Wells Kent. TN4 9AT. ISBN: 1 904798 764, ISBN: 978 1904798 767, UK., 2006.Kayaalp, O., Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Hacettepe-Taş Kitapçılık, 10. Baskı, Ankara., 2002.Mascaretti, O.A., Bacteria versus Antibacterial Agents. ISBN: 1-55581-258-9, ASM Press, Washington, D.C. 2003.Noyanalpan, N., Farmasötik ve Medisinal Kimya Ders Kitabı. Ankara: Ankara Üniversitesi Eczacılık Fakültesi Yayınları No: 49, 1978. Rx MediaPharma® İnteraktif İlaç Bilgi Kaynağı (Sürüm 14.0.0.0), 2014.The Merck Index Thirteenth Edition on CD-ROM, Copyright by Merck&Co;., Whitehouse Station, New Jersey, USA., 2001.Vardanyan, R., Hruby, V., Synthesis of Essential Drugs, ISBN-13: 978-0-44452166-8, ELSEIER B.V., Radarweg 29 P.O. Box 211, 1000 AE, Amsterdam, The Netherlands., p: 499, 2006.
Work Placement No laboratory practise
Aims of the Course

Weeks Learning Outcomes Topics Teaching Methods
Week - 1 Physical and chemical properties of aminoacids
Week - 2 Synthesis methods of aminoacids
Week - 3 The separation of chiral aminoacids
Week - 4 The preparation of aminoacid derivatives
Week - 5 The attachment of protecting groups to aminoacids
Week - 6 The attachment of protecting groups to amino group, carboxyl group and brached groups
Week - 7 Structures used as protecting group
Week - 8 The properties of amid structure
Week - 9 Synthesis of amid bonds
Week - 10 The activation of free functions
Week - 11 Procedure of acid Chloride and azide
Week - 12 Symmetrical and complex anhydrides,
Week - 13 The properties of peptides
Week - 14 The use of protecting groups’ aminoacids in peptide syntheses

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