Akademik Dersler - Tanıtım

Last Updated: 30/09/2026

Code - Course Title	Course Type	Laboratory + Practice	ECTS
FTE635 - Oral Drug Absorption and Evaluation Techniques	I. SEMESTER	3 +0	7.5

Language of Instruction	Türkçe
Course Type	Elective Courses
Course Instructor(s)	PROF. DR. MUSTAFA SİNAN KAYNAK
Mode of Delivery	The mode of delivery of this course is face to face.
Place of Delivery
Used Educational Platforms
Prerequisites	There is no prerequisite or co-requisite for this course.
Courses Recomended	There is no recommended optional programme component for this course.
Recommended Resources	Dressman J.B., Reppas C. Oral Drug Absorption: Prediction and Assessment, Second Edition, CRC Press Florida, USA, 2010.
Work Placement	Practical training is not required for this programme.
Aims of the Course

Weeks	Learning Outcomes	Topics	Teaching Methods
Week - 1		Introduction, definitions
Week - 2		Anatomy and Physiology of the GI Tract
Week - 3		Status of absorption determination in the regulations of health authorities
Week - 4		In vitro methods – I (PAMPA, other techniques)
Week - 5		Cell cultures – I (Caco-2)
Week - 6		Cell cultures – II (MDCK, other cells)
Week - 7		Ex-vivo methods (Ussing-Chamber, Everted gut sac technique)
Week - 8		In situ methods – I (Delusio technique, closed Loop technique)
Week - 9		In situ methods – II (Single pass intestinal perfusion technique)
Week - 10		In vivo methods – I (Tube techniques)
Week - 11		In vivo methods – II (Mass balance studies)
Week - 12		In vivo methods – III (Bioavailability studies)
Week - 13		Examples and applications – I
Week - 14		Examples and applications – II

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Assessment Method and Passing Requirements
	Quamtity	Percentage (%)
Toplam (%)