Catalog Content |
Introduction to Drug Metabolism; Phase I Reactions: Oxidation: Aromatic oxidation, Alkene oxidation, Oxidation of aliphatic carbon atoms, Oxidation of carbon-nitrogen system, Oxidation of carbon-oxygen system, Oxidation of carbon-sulfur system, Oxidation of alcohol and aldehyde, Other oxidative reactions; Reduction: Carbonyl reduction, Nitro reduction, Azo reduction, Other reductions; Hydrolysis; Phase II Reactions: Glucuronidation, Sulphation, Amino acid Conjugation, Glutathione Conjugation, Acetylation, Methylation; Drug Metabolism Studies; Effect of Metabolism on Drug Activity; Role of Drug Metabolism in Drug Development. |