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  • Microwave-Assisted Drug Synthesis Methods
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Course Title Code Compulsory/Elective Laboratory + Practice ECTS
Microwave-Assisted Drug Synthesis Methods FKM630 II. SEMESTER 3+0 7.5
Language of Instruction Türkçe
Course Type Elective Courses
Course Instructor(s) PROF. DR. AHMET ÖZDEMİR
Mode of Delivery Face to face
Prerequisites There is no prerequisite or co-requisite for this course.
Courses Recomended There is no recommended courses.
Recommended Reading List 1) S. A. Shetu, L. M. Sanchez-Palestino, G. Rivera, D. Bandyopadhyay, Medicinal bismuth: Bismuth-organic frameworks as pharmaceutically privileged compounds, Tetrahedron, 129, 133117, 2022.2) S. A. Shetu, D. Bandyopadhyay, Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies, Int. J. Mol. Sci. 23(7), 3706, 2022.3) J. Rock, D. Garcia, O. Espino, S. A. Shetu, M. J. Chan-Bacab, R. Moo-Puc, N. B. Patel, G. Rivera, D. Bandyopadhyay, Benzopyrazine-Based Small Molecule Inhibitors As Trypanocidal and Leishmanicidal Agents: Green Synthesis, In Vitro, and In Silico Evaluations, Front. Chem. Sec. Medicinal and Pharmaceutical Chemistry, 9, 725892, 2021.4) D. A. Rodrigues et al., Design, Synthesis and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors, J. Med. Chem. 59, 655, 2016.
Assessment methods and criteria Mid-Term Exam, Final, Homework
Work Placement Not applicable
Catalog Content Microwave Energy; History of Microwave: The evolution of microwave use: Fundamentals of microwave chemistry: Properties of microwaves and their interaction with matter, Microwave heating mechanisms, Super heating effect, Selectivity, Microwave synthesis methods, With solvent, Free solvent, Compressed, Solid support systems, Structure of the microwave device; Single and Multimode Devices, Benefits of microwave use, Examples of reactions using microwaves to obtain drug molecules, Biological effects of microwaves; Microwave Device Applications.

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