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Week - 1 |
Basic concepts in structure-activity relationships |
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Week - 2 |
Physicochemical properties, solubility |
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Week - 3 |
Partition coefficient, surface activity |
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Week - 4 |
Acid-base properties, ionization |
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Week - 5 |
Stereochemistry, electronic properties |
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Week - 6 |
Structural properties, steric properties |
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Week - 7 |
Molecular connectivity index, isosterism |
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Week - 8 |
Bioisosterism |
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Week - 9 |
Pharmacophore groups, metabolic stability |
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Week - 10 |
Drug-receptor interactions |
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Week - 11 |
Quantitative structure- activity relationships (QSAR) |
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Week - 12 |
Hansch analysis, Free-Wilson analysis |
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Week - 13 |
Fujita-Ban analysis, computer based methods |
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Week - 14 |
Drug design according to structure-activity relationships |
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