Catalog Content |
Basic Concepts in Structure-Activity Relationships; Physicochemical Properties: Solubility, Partition coefficient, Surface activity, Acid-base properties, Ionization, Stereochemistry, Electronic properties; Structural Properties: Steric properties, Molecular connectivity index, Isosterism, Bioisosterism, Pharmacophore groups, Metabolic stability, Drug-receptor relationships; Quantitative Structure- Activity Relationships (QSAR): Hansch analysis, Free-Wilson analysis, Fujita-Ban analysis; Computer Based Methods; Drug Design According to Structure-Activity Relationships. |