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  • Graduate School
  • Department of Pharmaceutical Chemistry
  • Master of Science (MS) Degree
  • Course Structure Diagram with Credits
  • Structure-Activity Relationships in Pharmaceutical Chemistry
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  • Will be able to list the properties of structure-activity relationships in pharmaceutical chemistry.
  • Will be able to define physicochemical properties in structure-activity relationships.
  • Describes structural features in structure-activity relationships.
  • Will be able to interpret the structure-activity relationships in drug molecules in terms of physicochemical properties.
  • Compares the structure-activity relationship in drugs in terms of solubility, partition coefficient and surface activity.
  • Distinguish the structure-activity relationship in drugs in terms of acid-base properties, ionization, stereochemistry, electronic properties.
  • Will be able to interpret the structure-activity relationships in drug molecules in terms of their structural properties.
  • Compares drug molecule and biological activity relationship in terms of steric properties, molecular connectivity index, isosterism, bioisosterism.
  • Distinguish between drug molecule and biological activity in terms of pharmacophore groups, metabolic stability and drug-receptor relationships.
  • Will be able to define quantitative structure-activity relationships (QSAR) in drug molecules.
  • Defines Hansch analysis, Free-Wilson analysis and Fujita-Ban analysis.
  • Reports computer-based methods.
  • Will be able to design new drug molecules according to structure-activity relationships.
  • Will be able to compare the functional groups on the drug molecule qualitatively and quantitatively.
  • Biologically interprets the structure-activity relationships of the functional groups on the drug molecule.

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