Week - 1 |
Introduction, definitions |
Week - 2 |
Anatomy and Physiology of the GI Tract |
Week - 3 |
Status of absorption determination in the regulations of health authorities |
Week - 4 |
In vitro methods – I (PAMPA, other techniques) |
Week - 5 |
Cell cultures – I (Caco-2) |
Week - 6 |
Cell cultures – II (MDCK, other cells) |
Week - 7 |
Ex-vivo methods (Ussing-Chamber, Everted gut sac technique) |
Week - 8 |
In situ methods – I (Delusio technique, closed Loop technique) |
Week - 9 |
In situ methods – II (Single pass intestinal perfusion technique) |
Week - 10 |
In vivo methods – I (Tube techniques) |
Week - 11 |
In vivo methods – II (Mass balance studies) |
Week - 12 |
In vivo methods – III (Bioavailability studies) |
Week - 13 |
Examples and applications – I |
Week - 14 |
Examples and applications – II |